No Doubt recorded a cover version of the song to promote their greatest hits album The Singles 1992–2003. Because the band was on hiatus, while lead singer Gwen Stefani recorded her solo debut album Love. Angel. Music. Baby., they decided to record a cover to avoid having to write a new song. The band listened to hundreds of songs and narrowed it down to "It's My Life" and INXS' 1982 song "Don't Change". No Doubt had doubts on recording a cover and contemplated writing new material. However, they decided on "It's My Life" after rehearsing the song with producer Nellee Hooper, referring to it as a "feel good" song. The song was nominated for Best Pop Performance by a Duo or Group with Vocal at the 47th Grammy Awards but lost to Los Lonely Boys' "Heaven". Jacques Lu Cont, the song's programmer, created the Thin White Duke mix of "It's My Life", which won the award for Best Remixed Recording, Non-Classical.

This version was featured on the video game Karaoke Revolution Volume 2. On December 9, 2008 it was also made available as downloadable content for the Rock Band series.